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Definition 2024


preplate

preplate

English

Noun

preplate (plural preplates)

  1. (anatomy) The structure, located near the pia, that develops into the cortical plate
    • 2015 July 29, Sébastien Roger et al., “Voltage-gated sodium channels and cancer: is excitability their primary role?”, in Frontiers in Pharmacology, volume 6, DOI:10.3389/fphar.2015.00152:
      This channel was proposed to increase the intracellular concentration of Ca 2+ through the participation of the NCX exchanger, thus triggering Ca 2+ -dependent signaling in the preplate neurons, leading to glutamate secretion and the development of the neocortex before functional synapses are formed (Platel et al., 2005 ).