- Burmese: မဲခေါင်မြစ် (mai:hkaungmrac)
- Chinese:
- Mandarin: (lower reaches) 湄公河 (zh) (Méigōng hé), (upper reaches) 瀾滄江 (zh), 澜沧江 (zh) (Láncāng jiāng)
- Finnish: Mekong (fi)
- French: Mékong (fr) m
- German: Mekong (de) m
- Hungarian: Mekong
- Italian: Mekong m
- Japanese: メコン川 (Mekon-gawa)
- Khmer: ទន្លេមេកុង (dtūənlēi meekoŋ), មេគង្គ (mékngkô)
- Khün:
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- Lao: ແມ່ນ້ຳຂອງ (lo) (mǣ nam khǭng), ນ້ຳຂອງ (nam khǭng)
- Lü: ᦓᧄᧉᦃᦸᧂ (nam²ẋoang)
- Northern Thai:
- Polish: Mekong (pl) m
- Portuguese: Mekong m
- Russian: Меко́нг m (Mekóng)
- Shan:
- Tai Dam:
- Thai: แม่น้ำโขง (mâe-náam kŏhng), แม่โขง (mâe-kŏhng), โขง (kŏhng)
- Tibetan: རྫ་ཆུ (rdza chu)
- Vietnamese: sông Mê Kông, sông Cửu Long, ("Great River") sông Lớn
- Zhuang: Dahmeizgunghhoz
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